SGEM Xtra: EBM and the Changingman

Date: July 20th, 2020 Guest Skeptic: Professor Simon Carley is Creator, Webmaster, owner and Editor in Chief of the St. Emlyn’s blog and podcast. He is Professor of Emergency Medicine at Manchester Metropolitan University and a Consultant in adult and paediatric Emergency Medicine at Manchester Foundation Trust. Dr. Carley is even verified on twitter as @EMManchester. Reference: Carley et al. Evidence-based medicine and COVID-19: what to believe and when to change. BMJ_EMJ July 2020 This is an SGEM Xtra episode. It was great to have one of the giants of the FOAMed world back on the SGEM. The last time Dr. Carely was on was on SGEM#148. The bottom line from that episode on skin glue for peripheral intravenous lines was: “Skin glue does appear to decrease the failure rate of IVs in patients admitted to hospital from the ED at 48 hours. We do not know if this is a good idea for all ED patients and we do not know the true effect size, but for high stakes cannulas that we really want to stay in this intervention should be considered.”  This SGEM Xtra is based on a wonderful article by Simon Carley, Daniel Horner, Rick Body, and Kevin Mackway-Jones published in the BMJ-Emergency Medicine Journal. The article was titled: Evidence-based medicine and COVID-19: what to believe and when to change. Simon and I discussed the what inspired him to write this article. It was great that it started with a definition of evidence-based medicine (EBM). They used the one proposed by Dr. David Sackett in 1996: “the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients” We gave a shout out to our friends Dr. Justin Morgenstern (First10EM) and Dr. Casey Parker (Broome Doc) on their recent podcast called EBM 2.0 with guest Dr. Senthi. It is important to remember the literature is just one of three pillars of EBM. There are many problems and limitations with medical research. This includes the dreaded p-value (dichotomization), biases (something that systematically moves us away from the “truth“), and the replication crisis. However, the other two pillars of EBM are equally as important. That includes the clinician’s judgment and the patient’s values and preferences. The first section of the article was about knowledge translation (KT) during the COVID19 pandemic. Listeners know the the SGEM is trying to cut the KT window down from over 10 years to less than one year using the power of social media. There is a study that quantify the KT gap being 17 years for 14% of high-quality, clinically relevant information to reach the patient (Morris, Wooding and Grant JRSM 2011). We then went on to talk about the precipitous decisions that are being made during COVID19 and give some examples. This is not a unique situation to a pandemic. There is something called intervention bias. This is the desire by the “medical community to intervene, whether it is with drugs, diagnostic tests, non-invasive procedures, or surgeries, when not intervening would be a reasonable alternative.”