“NAO Updates, Fall 2024” by Jeff Kaufman 🔸

This is a link post. It's been a busy season at the Nucleic Acid Observatory, and we have a lot to share since our last update. As always, If anything here is particularly interesting or if you’re working on similar problems, please reach out! Wastewater Sequencing We performed an initial analysis of untargeted sequencing data from aggregated airplane lavatory waste and municipal treatment plant influent that we collected and processed during our Fall 2023 partnership with CDC's Traveler-based Genomic Surveillance program and Ginkgo Biosecurity. We've now analyzed viral abundance and diversity in sequencing data across multiple sample types and wastewater-processing and sequencing protocols. Next steps include further investigating how protocol and sample-type affect specific viruses and bacteria, as well as understanding pathogen temporal dynamics seen in airport versus treatment-plant samples. We have continued to work with Pardis Sabeti's Lab at the Broad Institute to develop an optimized protocol for preparing [...] ---Outline:(00:22) Wastewater Sequencing(02:36) Pooled Individual Sequencing(03:36) Other Sampling Strategies(04:15) Nucleic Acid Tracers(04:50) Analysis of Sequencing Data(07:31) Organizational UpdatesThe original text contained 1 image which was described by AI. --- First published: October 18th, 2024 Source: https://forum.effectivealtruism.org/posts/ipErm2s9GvA8So86d/nao-updates-fall-2024 --- Narrated by TYPE III AUDIO. ---Images from the article:Apple Podcasts and Spotify do not show images in the episode description. Try Pocket Casts, or another podcast app.