The 2023 NKF Clinical Meeting Live Recording: Diuretic Draft

The Channelers went where no nephrology podcasters have gone before, recording in front of a live audience at the National Kidney Foundation Clinical Meeting in Austin. We had all eight Channelers doing a live podcast.We did a Freely Filtered-inspired draft of the best diuretics.The draft order:Leticia Rolon Anna Gaddy Joel TopfRoger Rodby Josh Waitzman Amy Yau JC Velez And Melanie HoenigReferencesJC Tolvaptan in Later-Stage Autosomal Dominant Polycystic Kidney DiseaseIntravenous conivaptan for the treatment of hyponatraemia caused by the syndrome of inappropriate secretion of antidiuretic hormone in hospitalized patients: a single-centre experienceRapidity of Correction of Hyponatremia Due to Syndrome of Inappropriate Secretion of Antidiuretic Hormone Following TolvaptanTolvaptan, a Selective Oral Vasopressin V2-Receptor Antagonist, for HyponatremiaJosh Review on amiloride development https://pubmed.ncbi.nlm.nih.gov/7039345/Toad bladder: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1351665/Amiloride derivatives that inhibit flagella: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544414/Amiloride as taste sensor: https://www.science.org/doi/10.1126/science.6691151Batlle on diabetes Insipidus: https://www.nejm.org/doi/full/10.1056/NEJM198502143120705?query=recirc_curatedRelated_articleAmiloride + ddavp for DI https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518801/Amy Treatment of refractory congestive heart failure and normokalemic hypochloremic alkalosis with acetazolamide and spironolactone.Acetazolamide reversibly inhibits water conduction by aquaporin-4Inhibition of Human Aquaporin-1 Water Channel Activity by Carbonic Anhydrase InhibitorsAcetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes InsipidusAcetazolamide in Lithium-Induced Nephrogenic Diabetes InsipidusIn Vivo Antibacterial Activity of AcetazolamideRoger50th anniversary of aldosteroneJoelSotagliflozin in Patients with Diabetes and Recent Worsening Heart FailureThe SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trialEffects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF)Empagliflozin and Heart failure: Diuretic and Cardiorenal EffectsAnnaClinical Results of Treatment of Diabetes Insipidus with Drugs of the Chlorothiazide SeriesTreatment of nephrogenic diabetes insipidus with hydrochlorothiazide and amilorideInfluence of renal nerves and sodium balance on the acute antidiuretic effect of bendroflumethiazide in rats with diabetes insipidusAntidiuretic effect of hydrochlorothiazide in lithium-induced nephrogenic diabetes insipidus is associated with upregulation of aquaporin-2, Na-Cl co-transporter, and epithelial sodium channelMajor Outcomes in High-Risk Hypertensive Patients Randomized to Angiotensin-Converting Enzyme Inhibitor or Calcium Channel Blocker vs DiureticWalsh AC, Moyes A. Intractable Congestive Heart Failure Successfully Treated With Southey Tubes. Can Med Assoc J. 1964 Jun 13;90(24):1375-6.Godwin TF, Gunton RW. Clinical trial of a new diuretic, furosemide: comparison with hydrochlorothiazide and mercaptomerin. Can Med Assoc J. 1965 Dec 18;93(25):1296-300.Gerber JG. Role of prostaglandins in the hemodynamic and tubular effects of furosemide. Fed Proc. 1983 Apr;42(6):1707-10.Schlatter E, Salomonsson M, Persson AE, Greger R. Macula densa cells sense luminal NaCl concentration via furosemide sensitive Na+2Cl-K+ cotransport. Pflugers Arch. 1989 Jul;414(3):286-90. doi: 10.1007/BF00584628.